Organic electrochemistry: Synthesis and functionalization of β-lactams in the twenty-first century

نویسندگان

چکیده

Abstract Organic electrochemistry is a technique that allows for the heterogeneous redox reactions avoiding both use of stoichiometric amounts reagents and resulting formation by-products. In fact, reagent in these electron, which naturally eco-friendly produces no side compounds. It therefore quite obvious can be classified as “green” technology. The this methodology synthesis β-lactams not novelty, but growing interest class biologically active compounds, due to discovery new fields application (after moment decrease antibiotic resistance) has been stimulus search more efficient electrochemical ways synthesize transform β-lactams. Thus, review deals with twenty-first-century applications electroorganic chemistry β-lactams, by analyzing first syntheses type (cyclization, cycloaddition, etc.) then manipulating β-lactam structure, using it synthon. Lastly, importance demonstrated study pilot plant scale reduction cephalosporanic acid derivative commercially important antibiotic.

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ژورنال

عنوان ژورنال: Heterocyclic Communications

سال: 2021

ISSN: ['0793-0283', '2191-0197']

DOI: https://doi.org/10.1515/hc-2020-0121